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4xx Client Error Safe to retry

421 Misdirected Request

The request was sent to a server that cannot produce a response for this authority.

What causes it

  • HTTP/2 connection coalescing: the client reused a connection for a second hostname on the same IP and certificate, and the server disagreed.
  • A TLS certificate covering multiple domains behind a server that is not configured for all of them.

How to fix it

  • Clients should retry on a fresh connection. On the server, make sure every hostname on a shared certificate is configured as a virtual host.

At a glance

Class
4xx Client Error
Reference
RFC 9110 §15.5.20
Standardised
Yes
Retry the request?
Yes, with backoff

Other 4xx client error codes

Back to the full HTTP status code reference